Only 5 percent of cancer research funds are spent on metastases, yet it kills...
On average, about five percent of total cancer research funding is spent on investigating metastases (the spread of cancer cells around the body) in Europe, yet metastatic disease is the direct or...
View ArticleMelanoma uses body's immune system to spread to lungs
(PhysOrg.com) -- The way melanoma cells use the immune system to spread and develop into lung tumors may lead to a therapy to decrease development of these tumors, according to Penn State researchers.
View ArticleOutcomes of communication about end-of-life care appear to differ between...
While both black patients and white patients appear to benefit from end of life discussions with their physician, black patients are less likely to experience end-of-life care that accurately reflects...
View ArticleMelanoma drug shrinks brain metastases in phase I/II study
A new drug being developed to treat potentially deadly melanoma skin cancers has shown a promising ability to shrink secondary tumors, known as metastases, in the brain in patients with advanced forms...
View ArticlePazopanib shows promise in Phase II trial for relapsed/refractory urothelial...
An ongoing Phase-II trial investigating a new, targeted therapy for metastatic urothelial cancer has generated promising early results, Italian researchers reported at the 35th Congress of the European...
View ArticleResearchers find pathway that drives spread of pediatric bone cancer in...
Researchers have identified an important signaling pathway that, when blocked, significantly decreases the spread of pediatric bone cancer.
View ArticleScientists turn a new leaf to discover a compound in daffodils that targets...
When looking for new ways to treat aggressive brain cancers, an international team of scientists turned a new leaf and "discovered" the lowly daffodil. A new research study published in the November...
View ArticleGreat genetic variation in pancreatic cancer, study shows
A new study published recently in Nature details the complexity of genetic variation found in pancreatic cancer cells. The ability to identify and understand the early mutations involved with the...
View ArticleNovel cancer drug has potential, study reports
(PhysOrg.com) -- Monthly injections of the drug in breast cancer patients whose disease had spread to the bone helped reduce pain and prevent complications with less toxicity than current treatments.
View ArticleTiny Trojan horses attack brain cancer cells
Scientists in Germany have developed a way of smuggling an anti-cancer drug past the protective blood-brain barrier and into brain tumours and metastases using a nanocarrier a tiny capsule specially...
View ArticleLess invasive method for determining stage of lung cancer shows benefits
A comparison of two strategies to determine the stage of suspected non-small cell lung cancer (NSCLC) finds that the less invasive method is more effective at identifying a type of lung cancer that has...
View ArticleStudy uses the patient's tumor to form vaccine
A new process for creating a personalized vaccine may become a crucial tool in helping patients with colorectal cancer develop an immune response against their own tumors. This dendritic cell (DC)...
View ArticleExpandable nanoparticles show promise in treating lethal abdominal cavity tumors
(PhysOrg.com) -- Too often, patients with ovarian cancer or mesothelioma develop metastases that spread within the abdominal cavity, and when that occurs, the chances of surviving beyond five years...
View ArticleResearchers uncover new risk factors for brain metastases in breast cancer...
Nearly one-fifth of all metastatic breast cancer patients develop brain metastases and have significantly shorter overall survival than patients who do not have brain involvement. One way to improve...
View ArticleDenosumab delayed time to first skeletal-related side effect
For patients with breast cancer and bone metastases, denosumab delayed skeletal-related side effects five months longer compared to those on zoledronic acid, according to results presented at the 33rd...
View ArticleDefective cell surface 'glue' is key to tumor invasion
A remarkable discovery into how tumour cells invade normal tissue should lead to vital diagnostic tools and help develop strategies to stop the spread of cancer cells. A new study by scientists at the...
View ArticleNew approaches refine molecular imaging for detecting cancer metastasis
(PhysOrg.com) -- Researchers may be a step closer to improving the detection of metastatic tumors in an organism - in real time - using a non-invasive approach that pairs an imaging agent with a...
View ArticleNovel immune system-based gene therapy induces strong responses in metastatic...
Researchers have found that a novel form of personalized therapy that genetically engineers a patient's own anti-tumor immune cells to fight tumors could treat metastatic melanoma and metastatic...
View ArticleNew drug for use in bone scans approved
The FDA has approved a New Drug Application (NDA) from the National Cancer Institute (NCI), part of the National Institutes of Health, for a new strength of a previously approved drug, Sodium Fluoride...
View ArticleLimited lymph node removal for certain breast cancer does not appear to...
Among patients with early-stage breast cancer that had spread to a nearby lymph node and who received treatment that included lumpectomy and radiation therapy, women who just had the sentinel lymph...
View ArticleEnzyme helps prepare lung tissue for metastatic development
A Massachusetts General Hospital (MGH) study has identified a new role for an important enzyme in preparing lung tissue for the development of metastases. Published in the early edition of Proceedings...
View ArticleBone drug zoledronic acid may help prevent spread of early lung cancer
A drug that is currently used to help treat bone metastases in patients with lung cancer could also be useful at an earlier stage of treatment, to prevent the cancer from spreading in the first place,...
View ArticleLymph node dissection is not essential in small screen-detected lung cancers,...
Lymph node dissection, the current standard surgical treatment for localized non-small cell lung cancers, may be unnecessary in certain screen-detected early stage cases , according to a study...
View ArticleInterventional radiologists provide hope in delaying growth, spread of breast...
The growth and spread of breast cancer tumors may be delayed with a promising treatment that combines two innovative strategies: blocking the enzyme needed to "energize" cancer cells and infusing a...
View ArticleBayer flags strong results of prostate cancer drug
German chemical and pharmaceutical group Bayer said Monday that its Alpharadin treatment for prostate cancer has shown positive results in advanced trials.
View ArticleB-Raf and C-Raf proteins turn mouse white
Mice with black fur that turns white? Specialist cancer researchers from Inserm, CNRS, the Institut Curie and the Université Paris-Sud have taken steps to better understand the development of skin...
View ArticleResearchers further refine 'NanoVelcro' device to grab single cancer cells...
(Phys.org)—Researchers at UCLA report that they have refined a method they previously developed for capturing and analyzing cancer cells that break away from patients' tumors and circulate in the...
View ArticleResearchers discover novel chemical that controls cell behavior
(Phys.org) —It's the spread of the original cancer tumor that kills most people. That's why cancer researchers vigorously search for drugs that can prevent metastases, the spread of cancer. The...
View ArticleIU surgeon's nanoparticle research takes inspiration from Greek mythology
An Indiana University School of Medicine breast cancer surgeon is pursuing research that will utilize glass, gold, nanotechnology and Greek mythology hoping to vanquish breast cancer that has...
View ArticleNovel molecules to target the cytoskeleton
The dysfunction of the cytoskeleton, a constituent element of the cell, is often associated with pathologies such as the onset of metastases. For this reason, it is a target of interest in numerous...
View Article
